Publications
Machtens, D.A., Hutchison, C.A., Stein, A.M., Ebherage, J., Willerding, J.M., Eschenburg, S., Shames, S.R., Reubold, T.F. 2026. Crystal structure of the Legionella pneumophila effector SidL (lpg0437) in complex with its metaeffector LegA11 (lpg0436). Virulence. 17(1):2646775
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Shames, S.R. 2024. Molecular mimicry sweetens the deal for MANagement of host mRNA translation and stress responses by Legionella pneumophila. Molecular Cell. 84(1):14-16
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Ngwaga, T., Chauhan, D., Salberg, A.G., Shames, S.R. 2023. Effector-mediated subversion of proteasome activator (PA)28αβ enhances host defense against Legionella pneumophila under inflammatory and oxidative stress conditions. PLoS Pathogens. 19:e1011473
Shames, S.R. 2023. Eat or be Eaten: Strategies used by Legionella to acquire host-derived nutrients and evade lysosomal degradation. Infection and Immunity. 91:e0044122
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Chauhan, D., Joseph, A.M., Shames, S.R. 2023. Intrabacterial regulation of a cytotoxic effector by its cognate metaeffector promotes Legionella pneumophila virulence. mSphere 8:e0055222
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Chauhan, D., Shames, S.R. 2021. Pathogenicity and Virulence of Legionella: Intracellular replication and host response. Virulence. 12(1):1122-1144.
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Ngwaga, T., Chauhan, D., and Shames, S.R. 2021. Mechanisms of effector-mediated immunity revealed by the accidental human pathogen Legionella pneumophila. Frontiers in Cellular and Infection Microbiology. 10: 593823
Joseph, A.M. and Shames, S.R. 2021. Affecting the effectors: Regulation of Legionella pneumophila effector function by metaeffectors. Pathogens. 10: 108
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Gilchrist, A.K., Smolensky, D., Ngwaga, T., Chauhan, D., Cox, S., Perumal, R., Noronha, L.E., and Shames S.R. 2020. High-polyphenol extracts from Sorghum bicolor attenuate replication of Legionella pneumophila within RAW 264.7 macrophages. FEMS Microbiology Letters. 367(7): fnaa053
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Joseph, A.M., Pohl, A.E., Ball, T.J., Abram, T.G., Johnson, D.K., Geisbrecht, B.V., and Shames, S.R. 2020 The Legionella pneumophila metaeffector Lpg2505 (MesI) regulates SidI-mediated translation inhibition and novel glycosyl hydrolase activity. Infection and Immunity. 88(5): e00853-19
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Ngwaga, T., Hydock, A.J., Ganesan, S., and Shames, S.R. 2019. Potentiation of cytokine-mediated restriction of Legionella intracellular replication by a Dot/Icm-translocated effector. Journal of Bacteriology. 201(14):e00755-18
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Shames, S.R. 2019. Screening targeted Legionella pneumophila mutant libraries in vivo using INSeq. Methods in Molecular Biology. 1921:123-144
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Shames, S.R., Liu, L., Havey, J.C., Schofield, W.B., Goodman, A.L., and Roy, C.R. 2017. Multiple Legionella pneumophila effector virulence phenotypes revealed through high-throughput analysis of targeted mutant libraries. Proceedings of the National Academy of Science USA. 114:E10446-E10454
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Arasaki, K., Mikami, Y., Shames, S.R., Inoue, H., Wakana, Y., Tagaya, M. 2017. Legionella Effector Lpg1137 shuts down ER-mitochondria communication through cleavage of Syntaxin 17. Nature Communications. 8:15406.
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Tørring, T., Shames, S.R., Cho, W., Roy, C.R., Crawford, J.M. 2017. Acyl-histidines: New N-acyl amides from Legionella pneumophila. ChemBioChem. 18(7): 638-46.
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Shames, S.R. and Finlay, B.B. 2012. Bacterial effector interplay: a new way to view effector function. Trends in Microbiology. 20(5):214-219.
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See the full list of Stephanie's publications at NCBI PubMed.
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