Publications
Ngwaga, T., Chauhan, D., Salberg, A.G., Shames, S.R. 2023. Effector-mediated subversion of proteasome activator (PA)28αβ enhances host defense against Legionella pneumophila under inflammatory and oxidative stress conditions. PLoS Pathogens. 19:e1011473
Shames, S.R. 2023. Eat or be Eaten: Strategies used by Legionella to acquire host-derived nutrients and evade lysosomal degradation. Infection and Immunity. 91:e0044122
Chauhan, D., Joseph, A.M., Shames, S.R. 2023. Intrabacterial regulation of a cytotoxic effector by its cognate metaeffector promotes Legionella pneumophila virulence. mSphere 8:e0055222
Chauhan, D., Shames, S.R. 2021. Pathogenicity and Virulence of Legionella: Intracellular replication and host response. Virulence. 12(1):1122-1144.
Ngwaga, T., Chauhan, D., and Shames, S.R. 2021. Mechanisms of effector-mediated immunity revealed by the accidental human pathogen Legionella pneumophila.Frontiers in Cellular and Infection Microbiology. 10: 593823
Joseph, A.M. and Shames, S.R. 2021. Affecting the effectors: Regulation of Legionella pneumophila effector function by metaeffectors. Pathogens. 10: 108
Gilchrist, A.K., Smolensky, D., Ngwaga, T., Chauhan, D., Cox, S., Perumal, R., Noronha, L.E., and Shames S.R. 2020. High-polyphenol extracts from Sorghum bicolor attenuate replication of Legionella pneumophila within RAW 264.7 macrophages. FEMS Microbiology Letters. 367(7): fnaa053
Joseph, A.M., Pohl, A.E., Ball, T.J., Abram, T.G., Johnson, D.K., Geisbrecht, B.V., and Shames, S.R. 2020 The Legionella pneumophila metaeffector Lpg2505 (MesI) regulates SidI-mediated translation inhibition and novel glycosyl hydrolase activity. Infection and Immunity. 88(5): e00853-19
Ngwaga, T., Hydock, A.J., Ganesan, S., and Shames, S.R. 2019. Potentiation of cytokine-mediated restriction of Legionella intracellular replication by a Dot/Icm-translocated effector. Journal of Bacteriology. 201(14):e00755-18
Shames, S.R. 2019. Screening targeted Legionella pneumophila mutant libraries in vivo using INSeq. Methods in Molecular Biology. 1921:123-144
Shames, S.R., Liu, L., Havey, J.C., Schofield, W.B., Goodman, A.L., and Roy, C.R. 2017. Multiple Legionella pneumophila effector virulence phenotypes revealed through high-throughput analysis of targeted mutant libraries. Proceedings of the National Academy of Science USA. 114:E10446-E10454
Arasaki, K., Mikami, Y., Shames, S.R., Inoue, H., Wakana, Y., Tagaya, M. 2017. Legionella Effector Lpg1137 shuts down ER-mitochondria communication through cleavage of Syntaxin 17. Nature Communications. 8:15406.
Tørring, T., Shames, S.R., Cho, W., Roy, C.R., Crawford, J.M. 2017. Acyl-histidines: New N-acyl amides from Legionella pneumophila. ChemBioChem. 18(7): 638-46.
Shames, S.R. and Finlay, B.B. 2012. Bacterial effector interplay: a new way to view effector function. Trends in Microbiology. 20(5):214-219.
See the full list of Stephanie's publications at NCBI PubMed.